Top 10 Pharmacy Management Solution Providers 2025

Redefining the Pharmacy Frontier: Inside the Evolution of Pharmacy Management

As healthcare is being rapidly transformed by digital innovation, value-based care models, and heightened patient expectations, pharmacy management has emerged as a powerful lever for improving both clinical and operational outcomes. What was once a back-office function is now a strategic hub—where medication safety, adherence, cost-efficiency, and care continuity converge.

Across the board, healthcare systems, hospitals, and independent pharmacies are turning to intelligent pharmacy management solutions to streamline workflows, automate inventory, enhance patient engagement, and deliver data-driven insights. Whether it’s leveraging AI for predictive adherence, integrating with EHRs for seamless e-prescribing, or building virtual pharmacy support for remote care—technology is reimagining the pharmacy like never before.

In this special edition of Medhealth Outlook Magazine, we shine a spotlight on the Top 10 Pharmacy Management Solution Providers who are setting new benchmarks in innovation, integration, and impact. These companies are not just solving the operational challenges of today—they’re building smarter, safer, and more responsive pharmacy systems for the future of healthcare.

From enterprise pharmacy platforms to patient-centered digital tools, this curated list recognizes the companies who are enabling better medication outcomes, optimizing resource use, and ensuring that every dose delivered contributes meaningfully to better health.

Alluma

Management:

Priyesh Patel

Designation:

General Manager

Headquarters:

Irving, TX

Website:

allumaco.com

Alluma is a provider-led, provider-focused Pharmacy Benefits Manager developed in collaboration between Vizient and Mayo Clinic. As the nation’s only member-owned, member-driven performance improvement company, Vizient is uniquely positioned to approach the PBM market with a provider lens. Mayo Clinic is focused on meeting patient needs and providing superior, evidence-based patient care. Mayo Clinic has offered pharmacy benefit expertise as a service to self-insured health plan clients across the country for more than 20 years and is a trusted source for health care and health information.

Benecard Services

Management:

Sandra Wolf

Designation:

VP Quality & Compliance

Headquarters:

Lawrenceville, NJ

Website:

benecard.com

Benecard Services, LLC has been administering carve-out, fixed rate insured prescription drug benefit programs since 1990. Benecard is a full service, in-house prescription benefit administrator that includes mail and specialty drug dispensing. They are a premiere nationwide Prescription Benefit Administrator headquartered in Lawrenceville, New Jersey, with regional locations in Ohio, Connecticut, and Pennsylvania.

CerpassRx

Management:

Greg Buscetto

Designation:

CEO

Headquarters:

The Colony, TX

Website:

cerpassrx.com

CerpassRx, formerly known as Healthcare Highways Rx, is the first true alternative to the traditional PBM model. Their focus is on patients and service, rather than profits. CerpassRx provide flexible solutions uniquely tailored for each of the clients including clinical, analytic and specialty management. CerpassRx has created a member-centric service model, when paired with their white glove client service, results in quality service that is unmatched in the industry.

Empirian Health

Management:

Shannon Speir

Designation:

President & CEO

Headquarters:

Montgomery, AL

Website:

empirian.com

Empirian Health is the leading provider of pharmaceutical spend management solutions for the Long-Term Care industry. With a powerful toolkit and expert in-house advisors, they tailor strategies to meet each partner’s unique goals. Known for their tested, trusted, and transparent approach, Empirian Health consistently delivers value and reliability across the LTC landscape.

Gateway Health Partners

Management:

Miranda Yeager

Designation:

President

Headquarters:

Canonsburg, PA

Website:

gatewayhealthpartners.com

Gateway Health has established itself as the largest independent provider of rebate and formulary management services in the United States. With a commitment to flexibility and transparency, the company offers unbundled, à la carte prescription cost management solutions, spanning rebates and retail pharmacy networks.

Health Accelerators

Management:

Joe Shields

Designation:

Co-Founder & President

Headquarters:

Exton, PA

Website:

healthaccelerators.com

Health Accelerators is the premier B2B marketing agency that helps leading professional services, data, technology and media solutions companies effectively reach, engage, and grow their business with pharma prospects and customers. The team deeply understand the pharma audience because they have worked for decades in the pharma roles clients need to target.

HealthPlan Data Solutions

Management:

Dale Wollschleger

Designation:

Founder

Headquarters:

Columbus, OH

Website:

hds-rx.com

HealthPlan Data Solutions (HDS) is an industry-leading pharmacy analytics company specializing in payment integrity, pharmacy data insights, and campaign management solutions. Their innovative solutions create a single source of truth, identifying, fixing, and monitoring pharmacy claims discrepancies to drive strategic and financial value. HDS connects pharmacy contracts and data, establishing order from complexity, enabling clients to focus on member care.

LIBERTY SOFTWARE

Management:

Jeremy Manchester

Designation:

President

Headquarters:

Southlake, TX

Website:

libertysoftware.com

Liberty Software has served community pharmacies for over 20 years, evolving from an independent service provider into a leading pharmacy technology company. Their flagship system, RXQ, empowers pharmacists across the U.S. to better serve patients. With a passionate team experienced in both pharmacy and tech, Liberty Software is committed to delivering user-friendly solutions and outstanding customer support.

Pharmacy Profiles

Management:

Mark Pilkington

Designation:

Executive Director

Headquarters:

Washington, DC

Website:

pharmacyprofiles.com

Pharmacy Profiles, a subsidiary of the American Pharmacists Association, is the nation’s first single-source repository of pharmacist providers. Built by pharmacists for pharmacists, it allows them to manage and verify their professional information in one place. The platform also supports employers, payers, and healthcare organizations in validating pharmacist credentials for expanding patient care roles.

ScriptPro

Management:

Mike Coughlin

Designation:

Chairman, Founder & CEO

Headquarters:

Mission, KS

Website:

scriptpro.com

With decades of experience in healthcare, ScriptPro has built a robust platform that addresses the operational, financial, and clinical challenges that pharmacies face. Its journey began with a vision to provide comprehensive, integrated solutions that streamline pharmacy operations and enhance patient care. Today, ScriptPro stand as a trusted partner, enabling pharmacies to grow their business and enable the best outcomes for their patients.