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Monday, September 26, 2022
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Third Harmonic Bio Goes Public with a $183 Million IPO; Plans to Make Your Healthcare Bid More Precise

Human beings boast a ton of abilities, and yet the greatest thing they have in their arsenal is the very tendency to grow on a consistent basis. This component, in particular, has allowed us to hit upon some huge milestones, with technology sticking out as a major member of the stated group. The reason why technology has been, since coming on to the scene, a notable presence in our lives is predicated upon its unique skill-set, which introduced us to a reality that we could have never imagined otherwise. However, if you dig deeper, it will quickly become clear that the whole runner was also inspired by how we used those skills in a real-world setting. The latter element was, in fact, what gave the creation a spectrum-wide presence, including a very well-timed appearance on our healthcare block. We call technology’s foray into healthcare well-timed because it came right when the sector was beginning to struggle against its own obsolete structure. This conundrum was fortunately resolved under the new regime, but even after achieving so much, the medtech linkup will just continue to produce all the right goods. The same has turned more and more evident over the recent past, and a new raise should only solidify its traces moving forward.

Third Harmonic Bio, a clinical-stage biopharmaceutical company, has successfully secured over $183.3 million from a recently-concluded IPO. According to certain reports, the biotech offered 10.9 million shares priced at $17 each. The share count is actually an interesting aspect here, as the company’s initial plan was to offer no more than 9 million shares. Talk about how Third Harmonic will use the newly-raised cash, it will invest around $80-90 million to facilitate the development of its lead molecule, THB001, which is designed to block KIT, a receptor that regulates mast cells, a type of immune cell. You see, mast cells are known have a big hand in many inflammatory conditions; therefore blocking it has seemingly helped the treatment for various disorders, such as asthma. Now, once you partner that with the ability to selectively block KIT, you also allow yourself to avoid any potential side effects, and that’s exactly what Third Harmonic wants to do.

At the moment, the Cambridge, Massachusetts-based company is working on a Phase 1b study for the stated molecule that has chronic urticaria as the lead disease target. The company hopes to report initial data from the Phase 1b study in the first half of 2023. As for the Phase 2 study, it is slated to begin in the first half of 2024. Moving on from the lead disease target, Third Harmonic will also use $30-40 million to make the drug a viable answer in terms of several other medical complications.

 

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